今日词汇
recurrence.复发
remission,缓解期，减轻期
psychosis精神病
bipolar disorder.躁郁症
blood plasma血浆；血清
原文（内容选自medical news today）
In a new pilot study that features in the journal Translational Psychiatry, an international team of researchers looked at metabolites as a potential tool to predict the risk of recurrence.
The research did not include anyone who was not in stable remission, had alcohol or drug use disorder, or had a secondary illness, such as anxiety, severe personality disorder, or symptoms of psychosis or bipolar disorder.
The researchers looked at each participant’s current metabolic state. Out of 612 potential metabolites, they found 399 in the blood plasma of both males and females.
Researchers found that changes in metabolism correlated with increased or decreased recurrence of major depressive episodes in this pilot study.
“The findings revealed an underlying biochemical signature in remitted [recurrent major depressive disorder] that set diagnosed patients apart from healthy controls,” says senior author Robert K. Naviaux, M.D., Ph.D., professor at the University of California San Diego School of Medicine. “These differences are not visible through ordinary clinical assessment,” Dr. Naviaux adds.
While validation studies are necessary, metabolic biomarkers may help evaluate the likelihood of a patient developing another depressive episode.
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